One upon a time, there was a curly-haired researcher who wanted to use serial dilutions to discover the dose of infectious bacteria that was not too strong and not too weak to kill 50% of affected crickets. She tried the strongest solution, but it was too strong, and killed all of the crickets. She tried the medium solution, but it was also too strong and killed almost all of the crickets. So she tried the weak solution, which was too weak and killed none of the crickets. Sadly, she did not find a dose that was just right.
The next week, she repeated this experiment using two medium-weak solutions. The first solution was too strong, and killed all of the crickets, the second solution was just right for females, yet killed all of the males.
The researcher was was all out of crickets, and after swearing and drinking some beer decided that she would have to repeat the experiment with only males and an even weaker series of solutions.
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